Research Articles

Browse the latest urology studies from PubMed

395 articles found

Medicine2026 Apr 10

Enarodustat combined with oral iron supplementation for iron-deficient non-dialysis-dependent chronic kidney disease anemia patients: Synergistic effects and safety.

Ying Lu, Ganru Jiang

This study aimed to evaluate the synergistic effect and safety of enarodustat combined with oral iron supplementation in the treatment of iron-deficient non-dialysis-dependent chronic kidney disease (...

HumansMaleFemaleRetrospective Studies+15
Medicine2026 Apr 10

The association between heart rate variability and early kidney damage: The mediating role of blood lipid levels among hypertensive patients in a single-center cohort study.

Ningning Xie, Fang Gao, Weidong Zhao +3 more

This study aimed to investigate the association between heart rate variability (HRV) and the risk of early kidney damage (EKD) among hypertensive patients, with particular emphasis on the mediating ro...

HumansMaleFemaleMiddle Aged+11
Medicine2026 Apr 10

Urinary bladder obstruction caused by fungal balls: Unusual computed tomography findings - a case report.

Lan Zhang, Chengye Hong

RATIONALE: Bladder fungal ball formation is a rare type of fungal infection, most commonly occurring in patients with diabetes or immunodeficiency. Only a few reports have described bladder fungal bal...

HumansMaleAgedTomography, X-Ray Computed+6
Medicine2026 Apr 10

Visceral adipose tissue and risk of kidney stones: Evidence from NHANES 2011-2018 and Mendelian randomization analysis.

Long Xia, Ben Wang, Binglei Jiang +3 more

Kidney stone is characterized by a high incidence and recurrence rate, and although previous studies have demonstrated that obesity increases the risk of nephrolithiasis, the causal relationship betwe...

HumansKidney CalculiMaleMendelian Randomization Analysis+9
Medicine2026 Apr 10

Cost-effectiveness analysis of Enfortumab vedotin and pembrolizumab for advanced urothelial carcinoma.

Hao Cheng, Jun Li, Ningying Mao

BACKGROUND: To evaluate the cost-effectiveness of Enfortumab vedotin and pembrolizumab (EVP) as a new first-line treatment option for advanced urothelial carcinoma compared to standard chemotherapy (g...

HumansCost-Benefit AnalysisAntibodies, Monoclonal, HumanizedQuality-Adjusted Life Years+12
Swiss medical weekly2026 Feb 25

Bilirubin interference in creatinine assays: cross-sectional analysis of the impact on the MELD score and CKD staging using Jaffe vs enzymatic methods.

Kathrin Frey, Joanna Gawinecka, Arnold Von Eckardstein +1 more

BACKGROUND: Reliable and accurate measurement of creatinine is essential for the estimation of kidney function (eGFR) and for survival prediction with the model of the end-stage liver disease (MELD) s...

HumansBilirubinCreatinineCross-Sectional Studies+9
Journal of environmental management2026 Apr 15

Linking groundwater chemistry to bovine kidney damage: A one health perspective on fluoride-DOM-hard water interactions in CKDu-hotspots.

H M S Wasana, G D R K Perera, I A M P Ileperuma +5 more

The 'One Health' approach to CKDu research has not yet reported the impact of drinking water exposure on bovine kidney functions in CKDu endemic areas. This study investigated the associations of fluo...

AnimalsCattleFluoridesGroundwater+4
Wiadomosci lekarskie (Warsaw, Poland : 1960)2026

Urinary tract infections in patients undergoing orthopaedic procedures: A contemporary review (2021-2026).

Mateusz Kaczmarski, Zeeshan Zulfiqar, Vasu Duangudomdej +3 more

Urinary tract infections are one of the most frequent healthcare-associated infections representing a relevant postoperative complication in orthopedics patients. These infections are associated with ...

HumansUrinary Tract InfectionsOrthopedic ProceduresRisk Factors+1
Journal of ethnopharmacology2026 Jul 15

Grape seed proanthocyanidin extract suppresses bladder cancer by dual blockade of IMPDH1/2-mediated purine and pyrimidine nucleotide biosynthesis.

Xiang Han, Shuhong Dong, Yingwen Wang +5 more

ETHNOPHARMACOLOGICAL RELEVANCE: Grape seed proanthocyanidin extract (GSPE), derived from Vitis vinifera L., has been used in traditional European and Mediterranean medicine to treat inflammation, vasc...

ProanthocyanidinsAnimalsUrinary Bladder NeoplasmsHumans+15
European journal of pharmacology2026 Apr 28

Klotho-derived peptide preserves erectile function by limiting fibrosis, oxidative stress, and apoptosis of penile smooth muscle cells in cavernous nerve injured-rats through suppression of the TGF-β1/TGF-β type II receptor signaling.

Yuhang Xi, Guangye Han, Xiaojie Li +4 more

Patients with prostate cancer frequently complain of erectile dysfunction (ED) after radical prostatectomy (RP). Corporal fibrosis and apoptosis following cavernous nerve injury (CNI) significantly co...

AnimalsMaleOxidative StressApoptosis+12
International journal of urology : official journal of the Japanese Urological Association2026 Apr

Prognostic Significance of Hypoalbuminemia in Maintenance Avelumab Therapy After First-Line Chemotherapy for Metastatic Urothelial Carcinoma: A Multicenter Real-World Study (YUSHIMA Study).

Rie Muta, Hiroshi Fukushima, Hajime Tanaka +14 more

OBJECTIVES: Maintenance avelumab therapy after first-line induction chemotherapy is a viable option in the evolving treatment paradigm for metastatic urothelial carcinoma (mUC); however, the clinical ...

HumansMaleAgedFemale+15
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica2026 Apr

Evaluation of Epithelial Integrity in Human Precision-Cut Kidney Slices.

Gitte A Pedersen, Benjamin B Green, Camilla Merrild +6 more

Renal epithelial cells are pivotal in renal regulation of body fluid and electrolyte balance. While rodent models are commonly used to study renal physiology, species-specific differences limit their ...

HumansAquaporin 2Epithelial CellsKidney+6